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The agents used and the final concentrations found to be optimum for assessing platelet aggregation were 2 ug/mL collagen for patients taking aspirin 81 mg/day and 2 umol/L ADP for patients taking ticlopidine 200 mg/ d.In 17(10%)of the 159 outpatients,platelet aggregation was not adequately reduced because of noncompliance with their antiplatelet therapy.This study indicated that monitoring of compliance is important for outpatients on antiplatelet therapy.It is best if platelet aggregation can be checked, but when this is impossible it is necessary to assess compliance periodically and provide patient guidance. |
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